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• CAS 481-74-3 Chrysophanic acid

  Chrysophanol is an anthraquinone that has been found in R. palmatum and has diverse biological activities. It induces necrosis in J5 human liver cancer cells when used at concentrations of 25, 50, 75, 100, and 200 μM. Chrysophanol (5, 10, and 50 μM) reduces LPS-induced production of nitric oxide (NO) and prostaglandin E2 (PGE2; ) and inhibits LPS-induced DNA oxidation in BV-2 microglia. In vivo, chrysophanol (5 mg/kg) decreases colonic levels of IL-6 and activation of NF-κB and reduces weight loss, diarrhea, and rectal bleeding in a mouse model of colitis induced by dextran sulfate (DSS; ). Chrysophanol (0.1, 1, and 10 mg/kg) increases survival, reduces brain tissue loss, and ameliorates motor balance deficits in a mouse model of ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO).

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Product Introduction:

Product Name: Chrysophanic acid

Synonyms: CHRYSOPHANIC ACID;CHRYSOPHANOL;RHUBARB EXTRACT;1,8-dihydroxy-3-methyl-10-anthracenedione;1,8-Dihydroxy-3-methyl-9,10-anthraquinone;1,8-dihydroxy-3-methyl-anthraquinon;2-Methyl-4,5-dihydroxyanthraquinone;3-Methyl-1,8-dihydroxyanthraquinone

CAS: 481-74-3

MF: C15H10O4

MW: 254.24

EINECS: 207-572-2

Product Categories: Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Aloe Vera;Bioactive Small Molecules;Building Blocks;C15 to C38;Carbonyl Compounds;Cell Biology;Chemical Synthesis;DIG-DY;Ketones;Nutrition Research;Organic Building Blocks;Anthraquinones, Hydroquinones and Quinones;The group of Polydatin;Phytochemicals by Plant (Food/Spice/Herb);chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors

form crystalline

color yellow-orange