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• CAS 129741-57-7 PULCHINENOSIDE B4

  Description    Pulchinenoside B4 is a triterpenoid glycoside that has been found in P. chinensis and has diverse biological activities. It inhibits cisplatin-induced apoptosis, increases in reactive oxygen species (ROS) production, and decreases in superoxide dismutase (SOD) and catalase activities in HEK293 cells when used at concentrations of 6 and 12 μM. Pulchinenoside B4 (50 and 100 mg/kg twice per day) prevents increases in plasma blood urea nitrogen (BUN) and creatinine levels, markers of kidney injury, in a mouse model of cisplatin-induced nephrotoxicity. It prevents xylene-induced ear edema in mice in a dose-dependent manner. Pulchinenoside B4 (50 mg/kg) inhibits LPS-induced increases in serum TNF-α, IL-6, and IL-1β levels a mouse model of LPS-induced systemic inflammation.

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Product Introduction:

Product Name: PULCHINENOSIDE B4

Synonyms: PULCHINENOSIDE B4;Anemoside B4 Pulchinenoside B4;Chinensioside A;Pulchinenoside C;Anemoside B4;Pulsatilla saponin B4;Pulchinenoside B4, 98%, from Pulsatilla chinensis (Bunge) Regel;AnemosideB4 129741-57-7

CAS: 129741-57-7

MF: C59H96O26

MW: 1221.38

form Powder

pka 12.50±0.70(Predicted)

color White to light yellow