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• CAS 118-34-3 ELEUTHEROSIDE B

  Description Syringin is a phenylpropanoid glycoside first isolated from A. senticosus that enhances acetylcholine release in pancreatic cells leading to an increase in insulin release through the muscarinic M3 receptor. Syringin dose-dependently (50, 75, and 100 μg/kg, i.v.) decreases plasma glucose levels and increases insulin-like immunoreactivity and C-peptide in rats, and these effects last at least 60 minutes. In a rat model of type 1 diabetes, it decreases plasma glucose and increases β-endorphin release from the adrenal medulla. Syringin increases autophagy through AMP-activated protein kinase α (AMPKα) activation concomitant with preventing the progression of cardiac hypertrophy in mice following aortic banding. It also has immunomodulatory effects, likely due to its metabolite sinapyl alcohol.

  
  

  
  

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Product Introduction:

Product Name: ELEUTHEROSIDE B

Synonyms: SYRINGIN;SYRINGINE;SYRINGOSIDE;LIGUSTRIN;ILACIN;ELEUTHEROSIDE B;Ciwujianoside-B(ELEUTHEROSIDE B);Syringin (eleutheroside B)

CAS: 118-34-3

MF: C17H24O9

MW: 372.37

EINECS: 601-519-0

Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Phenylpropanoids;Cardioglycosides & Glycosides;Standardized plant extract

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