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• CAS 82854-37-3 ECHINACOSIDE

  Echinacoside is a phenylethanoid glycoside that has been found in Echinacea and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals (EC50 = 6.6 μM in a cell-free assay). Echinacoside (10 μg/ml) inhibits hydrogen peroxide-induced production of reactive oxygen species (ROS) and apoptosis in PC12 cells. It reduces increases in plasma alanine aminotransferase (ALT), TNF-α, IL-1β, IL-16, and IL-10 levels and hepatocyte apoptosis induced by LPS/D-galactosamine in a mouse model of acute liver injury when administered at a dose of 60 mg/kg. Echinacoside (20 mg/kg per day for 15 days) prevents loss of dopaminergic neurons in the substantia nigra pars compacta and decreases in striatal dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) levels in a mouse model of MPTP-induced Parkinson''s disease. It also improves motor performance in the rotarod test in the same model.

  
  

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Product Introduction:

Product Name: ECHINACOSIDE

Synonyms: (1-3)-o-(beta-d-glucopyranosyl-(1-6))-,4-(3-(3,4-dihydroxyphenyl)-2-propenoat;2-(3,4-dihydroxyphenyl)ethylo-6-deoxy-alpha-l-mannopyranosyl-glucopyranosid;beta-d-e;ECHINACOSIDE;ECHINACOSIDE(AMERICAN HERBAL PHARMACOPOEIA);ECHINACOSIDE 20% DESERTLIVING CISTANCHE P.E.;Cistanche tubulosa;Echinacoside/CH80711

CAS: 82854-37-3

MF: C35H46O20

MW: 786.73

EINECS: 240-851-7

Product Categories: chemical reagent;pharmaceutical intermediate;Sugars, Carbohydrates & Glucosides;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract

form powder

color White-beige