CAS 1953-54-4 5-Hydroxyindole
Product Name: 5-Hydroxyindole
Synonyms: 5-Hydroxy-1H-indole;Hydroxy-5 indole;hydroxy-5indole;TIMTEC-BB SBB004214;1H-INDOL-5-OL;5-HYDROXYINDOLE;5-INDOLOL;INDOL-5-OL
CAS: 1953-54-4
MF: C8H7NO
MW: 133.15
EINECS: 217-782-6
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Use ;Reactant for preparation of (oxoimidazolidinyl/oxopyrimidinyl)benzenesulfonates as antitumor agents and tubulin inhibitors1• ;Reactant for preparation of anthranilic acids2• ;Reactant for preparation of indole compounds as dopamine D2 receptor antagonists3• ;Reactant for preparation of naphthalimide- or carbazole-containing human β-adrenoceptor ligands4• ;Reactant for preparation of melanins as nature-inspired radioprotectors5• ;Reactant for preparation of 5-vinyl-3-pyridinecarbonitriles as PKCθ inhibitors6
Uses 5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptophan (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets.
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