CAS 133514-43-9 Exendin-3 (9-39) amide
Description Exendin-3 (9-39) amide is a truncated form of the exendin-4 peptide that acts as a potent competitive antagonist for the glucagon-like peptide 1 receptor (GLP-1R; Kd = 1.7 nM in CHL cells transfected with cloned human GLP-1). It inhibits exendin-3-induced increases in cAMP levels in guinea pig pancreas cells (IC50 = 20 nM). Exendin-3 (9-39) amide administration in the hypothalamus (10 and 100 μg, i.c.v.) reverses GLP-1 inhibition of feeding behavior in rats.
Uses Biological probe.
Uses Exendin-3 (9-39) is a potent and selective GLP-1 receptor antagonist.
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Product Name: Exendin-3 (9-39) amide
Synonyms: ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2;H-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2;EXENDIN 3 (9-39);EXENDIN-3 (9-39) AMIDE;EXENDIN (9-39);EXENDIN (9-39) AMIDE;EXENDIN [9-39] PEPTIDE;EXENDIN FRAGMENT 9-39
CAS: 133514-43-9
MF: C149H234N40O47S
MW: 3369.76
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