• 

• CAS 497-76-7 Arbutin

  Arbutin is a glycosylated hydroquinone that has been found in Arctostaphylos plants and has diverse biological activities, including tyrosinase inhibitory, antioxidant, and anti-inflammatory properties. It inhibits human tyrosinase activity in crude tyrosinase solution isolated from human melanocytes (IC50s = 5.7 and 18.9 mM using L-tyrosine and L-DOPA as substrates, respectively) as well as in intact melanocytes (IC50 = 0.5 mM). Arbutin (50 μM) inhibits hemolysis induced by the free radical generator AAPH in sheep erythrocytes and inhibits AAPH-induced decreases in cell viability in cultured human skin fibroblasts when used at concentrations greater than 125 μM. In an LPS-induced rat model of acute lung injury, arbutin (50 mg/kg) prevents increases in IL-1β, IL-6, and TNF-α levels in lung tissue and serum. Formulations containing arbutin have been used in the treatment of hyperpigmentation disorders.

  Price on request

  REQUEST NOW

Product Introduction:

Product Name: Arbutin

Synonyms: 4-hydroxyphenyl-beta-d-glucopyranosid;beta-arbutin;Hydroquinone β-D-glucopyranoside;Arbutin (natural);4-HYDROXYPHENYL-BETA-D-GLUCOPYRANOSIDE;4-(β-D-Glucopyranosyloxy)phenol;arbutin,beta-arbutin;4-hydroxyphenyl β-D-galactopyranoside

CAS: 497-76-7

MF: C12H16O7

MW: 272.25

EINECS: 207-850-3

Product Categories: Uva, Ursi, p-Arbutin, Hydroquinone β-D-glucopyranoside;natural product;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;Biochemistry;Glucose;Glycosides;Sugars;Plant extracts;Herb extract;standardized herbal extract;Plant extract;Natural Plant Extract;Inhibitors;497-76-7;Glycon Biochem

form Solid

pka 10.10±0.15(Predicted)

color White