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• CAS 110880-55-2 (SAR9,MET(O2)11)-SUBSTANCE P

  Uses Sar9,Met(O2)11]-Substance P is a potent and selective NK1 tachykinin receptor agonist (1). The NK1 tachykinin receptor is a member of the G-protein coupled receptor family and can be found in neurons, brainstem, and vascular endothelial cells (2,3). NK1 tachykinin receptor is a therapeutic target for pancreatic cancer (4).

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Product Introduction:

Product Name: (SAR9,MET(O2)11)-SUBSTANCE P

Synonyms: (2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfonyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]pentanediamide;[Sar9,Met(O2)11]-Substance P,Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met[O2]-NH2?, >98%;[SAR9,MET(O2)11]-SUBSTANCE P?, >98%;H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-SAR-LEU-MET(O2)-NH2;ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-SAR-LEU-MET(O2)-NH2;(SAR9,MET(O2)11)-SUBSTANCE P;RPKPQQFFSARLM(O2);[SAR9 ,MET(O2 )11 ]-SUBSTANCE P HIGHLY SPECIFIC NEUROKININ NK1 RECEPTOR 97+%

CAS: 110880-55-2

MF: C64H100N18O15S

MW: 1393.66